The article explores the use of ketamine as a rapid-acting treatment for major depressive disorder and treatment-resistant depression. It highlights how ketamine can provide significant symptom relief within hours, contrasting with traditional antidepressants that may take weeks. The authors discuss the neurobiological mechanisms involved, including NMDA receptor antagonism and the role of glutamate, while also noting safety and efficacy concerns. The findings support ketamine's potential as a promising option for patients with limited treatment success.

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This article reviews the potential of ketamine as a rapid-acting treatment for major depressive disorder (MDD) and its mechanisms of action. The authors discuss the promising effects of ketamine on depression, particularly in treatment-resistant cases, highlighting its ability to reduce suicidal ideation and improve mood within hours. They emphasize the need for further research to establish optimal dosing, delivery methods, and long-term effects, advocating for ketamine's integration into depression treatment protocols as a valuable option for patients.

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The article examines the efficacy of ketamine as a treatment for post-traumatic stress disorder (PTSD), highlighting its rapid antidepressant effects. It discusses ketamine's mechanisms of action, including its impact on glutamate signaling, and its potential to alleviate symptoms of PTSD and depression. The review emphasizes the need for further research to optimize treatment protocols and understand the long-term effects of ketamine therapy. Overall, it positions ketamine as a promising option in the management of PTSD.

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